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References
Burzyn D, Benoist C, Mathis D . Regulatory T cells in nonlymphoid tissues. Nat Immunol 2013; 14: 1007–1013.
Zhou X, Tang J, Cao H, Fan H, Li B . Tissue resident regulatory T cells: novel therapeutic targets for human disease. Cell Mol Immunol 2015; 12: 543–552.
Ryba‐Stanislawowska M, Stanislawowski M, Mysliwska J . Effector and regulatory T cell subsets in diabetes‐associated inflammation. Is there a connection with ST2/IL‐33 axis? Perspective. Autoimmunity 2014; 47: 361–371.
Cipolletta D, Kolodin D, Benoist C, Mathis D . Tissular Tregs: a unique population of adipose‐tissue‐resident Foxp3+CD4+ T cells that impacts organismal metabolism. Semin Immunol 2011; 23: 431–437.
Vasanthakumar A, Moro K, Xin A, Liao Y, Gloury R, Kawamoto S et al. The transcriptional regulators IRF4, BATF and IL‐33 orchestrate development and maintenance of adipose tissue‐resident regulatory T cells. Nat Immunol 2015; 16: 276–285.
Zeng H, Zhang R, Jin B, Chen L . Type 1 regulatory T cells: a new mechanism for the peripheral immune tolerance. Cell Mol Immunol 2015; 12: 566–571.
Kim HJ, Verbinnen B, Tang X, Lu L, Cantor H . Inhibition of follicular T‐helper cells by CD8+ regulatory T cells is essential for self tolerance. Nature 2010; 467: 328–332.
Peterson RA . Regulatory T‐cells: diverse phenotypes integral to immune homeostasis and suppression. Toxicol Pathol 2012; 40: 186–204.
Jonuleit H, Schmitt E . The regulatory T cell family: distinct subsets and their interrelations. J Immunol 2003; 171: 6323–6327.
Shevach EM, Thornton AM . tTregs, pTregs, and iTregs: similarities and differences. Immunol Rev 2014; 259: 88–102.
Sage PT, Francisco LM, Carman CV, Sharpe AH . The receptor PD‐1 controls follicular regulatory T cells in the lymph nodes and blood. Nat Immunol 2013; 14: 152–161.
Liston A, Gray DH . Homeostatic control of regulatory T cell diversity. Nat Rev Immunol 2014; 14: 154–165.
Cretney E, Xin A, Shi W, Minnich M, Masson F, Miasari M et al. The transcription factors Blimp‐1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat Immunol 2011; 12: 304–311.
Cipolletta D, Feuerer M, Li A, Kamei N, Lee J, Shoelson SE et al. PPAR‐γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 2012; 486: 549–553.
Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009; 15: 930–939.
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Hu, Z., Zhao, W. The IL‐33/ST2 axis is specifically required for development of adipose tissue‐resident regulatory T cells. Cell Mol Immunol 12, 521–524 (2015). https://doi.org/10.1038/cmi.2015.49
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DOI: https://doi.org/10.1038/cmi.2015.49
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