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Neurodevelopmental Outcome at 8 Months and 4 Years among Infants Born Full-Term Small-for-Gestational-Age

Journal of Perinatology volume 24, pages 505–514 (2004)Cite this article

Abstract

OBJECTIVES: To examine the association between intrauterine growth restriction and neurodevelopmental outcome among full-term small-for-gestational-age (SGAT) infants at 8 months and 4 years of age.

STUDY DESIGN: Growth parameters at birth and test scores on measures of neurodevelopmental function for 3922 children born SGAT were compared with those of 29,369 children born appropriately grown-for-gestational-age term from similar economic backgrounds. Additional within-SGAT/economic group comparisons were made for 1684 SGAT infants with symmetric undergrowth at birth and 2034 SGAT infants with asymmetric undergrowth at birth.

RESULTS: Regardless of socioeconomic background, infants born SGAT were found to be at significantly increased risk for neurodevelopmental difficulties at 8 months and at 4 years of age. Few within SGAT/socioeconomic group differences in neurodevelopmental outcome appeared to be associated with specific pattern of growth restriction at birth.

CONCLUSIONS: The present findings provide further evidence of the individual and public health impact of SGAT birth.

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Authors and Affiliations

  1. Department of Human and Community Development, University of California, Davis, Sacramento, CA, USA

    Laura L Jelliffe-Pawlowski PhD

  2. Department of Pediatrics, MIND Institute, University of California, Davis, Sacramento, CA, USA

    Robin L Hansen MD

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  1. Laura L Jelliffe-Pawlowski PhD
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  2. Robin L Hansen MD
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Appendix A

Appendix A

See Table A1

Table a1 Sample-specific birth weight norms (in g) for black and white full-term singleton births who were participants in the National Collaborative Perinatal Projecta
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Jelliffe-Pawlowski, L., Hansen, R. Neurodevelopmental Outcome at 8 Months and 4 Years among Infants Born Full-Term Small-for-Gestational-Age. J Perinatol 24, 505–514 (2004). https://doi.org/10.1038/sj.jp.7211111

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