Abstract
OBJECTIVE: To report our experience with thrombolytic agents in the management of two infants with silicone central venous catheters that had adhered to the vein wall as a result of infection with Malassezia furfur.
STUDY DESIGN: Case review of two very low birth weight infants with adherent central venous catheters.
RESULTS: Treatment with urokinase and tissue plasminogen activator facilitated the removal of these catheters without breakage or surgical intervention.
CONCLUSIONS: Thrombolytic agents should be considered as a treatment of adhered catheters, as well as of occluded catheters.
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Nguyen, S., Lund, C. & Durand, D. Thrombolytic Therapy for Adhesion of Percutaneous Central Venous Catheters to Vein Intima Associated With Malassezia furfur Infection. J Perinatol 21, 331–333 (2001). https://doi.org/10.1038/sj.jp.7200517
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DOI: https://doi.org/10.1038/sj.jp.7200517