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Alzheimer's disease

Attack on amyloid-β protein

An antibody therapy markedly reduces aggregates of amyloid-β, the hallmark protein of Alzheimer's disease, and might slow cognitive decline in patients. Confirmation of a cognitive benefit would be a game-changer. See Article p.50

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Figure 1: The amyloid hypothesis.

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References

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Correspondence to Eric M. Reiman.

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Competing interests

E.M.R. is a principal investigator of the Alzheimer’s Prevention Initiative (API), which is involved in the evaluation of anti-Aβ and other promising Alzheimer’s prevention therapies.

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Reiman, E. Attack on amyloid-β protein. Nature 537, 36–37 (2016). https://doi.org/10.1038/537036a

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