The genome sequence of a fetus can be inferred from the relative numbers of variants of DNA sequences in a pregnant woman's blood. This advance in non-invasive diagnostics comes with some ramifications. See Article p.320
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Bianchi, D. W. & Ferguson-Smith, M. A. Prenat. Diagn. 30, 601–604 (2010).
Fan, H. C. et al. Nature 487, 320–324 (2012).
Lo, Y. M. et al. Lancet 350, 485–487 (1997).
Fan, H. C. et al. Nature Biotechnol. 29, 51–57 (2011).
Kitzman, J. O. et al. Nature Biotechnol. 29, 59–63 (2011).
Kitzman, J. O. et al. Sci. Transl. Med. 4, 137ra76 (2012).
Bianchi, D. W. Nature Med. 18, 1041–1051 (2012).
Lo, Y. M. et al. Sci. Transl. Med. 2, 61ra91 (2010).
Benn, P. et al. Prenat. Diagn. 32, 1–2 (2012).
The author is chair of the clinical advisory board of Verinata Health. She receives honoraria and equity from the company.
Rights and permissions
About this article
Cite this article
Bianchi, D. Fetal genes in mother's blood. Nature 487, 304–305 (2012). https://doi.org/10.1038/487304a
This article is cited by
Cell Communication-mediated Nonself-Recognition and -Intolerance in Representative Species of the Animal Kingdom
Journal of Molecular Evolution (2020)