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Tumour biology

Skin-cancer stem cells outwitted

Skin-cancer stem cells secrete a factor that organizes a blood-supply system to fuel tumour growth. But the same factor has another sinister function — it stimulates the stem cells to propagate uncontrollably. See Letter p.399

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Figure 1: Two-pronged effects of VEGF.

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Correspondence to Salvador Aznar Benitah.

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Benitah, S. Skin-cancer stem cells outwitted. Nature 478, 329–330 (2011). https://doi.org/10.1038/478329a

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