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HIV

Going for the watchman

A protein called SAMHD1 seems to hinder the infection of key cells of the immune system by HIV-1. Cousins of this virus, however, produce a factor that overcomes the protective effects of SAMHD1. See Letters p.654 & p.658

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Figure 1: Vpx, SAMHD1 and viral replication1,2.

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Correspondence to Michael Emerman.

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Lim, E., Emerman, M. Going for the watchman. Nature 474, 587–588 (2011). https://doi.org/10.1038/474587a

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