Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cell signalling

Why fasting worms age slowly

Lipids of the N-acylethanolamine family mediate cell signalling across a wide range of organisms. In nematode worms, they translate food availability into fundamental choices about development that affect lifespan. See Letter p.226

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: N-Acylethanolamines, feeding behaviour and lifespan.

FROM BOTTOM: K. WOTHE/MINDEN PICTURES/FLPA; S. STAMMERS/SPL; K. TELNES/IMAGEQUESTMARINE.COM; G. LACZ/FLPA; REINHARD/ARCO/NATUREPLCOM

References

  1. Fontana, L., Partridge, L. & Longo, V. D. Science 328, 321–326 (2010).

    Article  ADS  CAS  Google Scholar 

  2. Lucanic, M. et al. Nature 473, 226–229 (2011).

    Article  ADS  CAS  Google Scholar 

  3. Devane, W. A. et al. Science 258, 1946–1949 (1992).

    Article  ADS  CAS  Google Scholar 

  4. Matias, I., Bisogno, T. & Di Marzo, V. Int. J. Obes. 30, S7–S12 (2006).

    Article  CAS  Google Scholar 

  5. Fu, J. et al. Nature 425, 90–93 (2003).

    Article  ADS  CAS  Google Scholar 

  6. Berdyshev, E. V. et al. World Rev. Nutr. Diet. 88, 207–214 (2001).

    Article  CAS  Google Scholar 

  7. Kilaru, A. et al. Chem. Biodivers. 4, 1933–1955 (2007).

    Article  CAS  Google Scholar 

  8. Elphick, M. R. & Egertová, M. Handb. Exp. Pharmacol. 168, 283–297 (2005).

    Article  CAS  Google Scholar 

  9. Pertwee, R. G. et al. Pharmacol. Rev. 62, 588–631 (2010).

    Article  CAS  Google Scholar 

  10. McPartland, J. M., Norris, R. W. & Kilpatrick, C. W. Gene 397, 126–135 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vincenzo Di Marzo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

De Petrocellis, L., Di Marzo, V. Why fasting worms age slowly. Nature 473, 161–162 (2011). https://doi.org/10.1038/473161a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/473161a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing