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Macrophages limit chemotherapy

A major hurdle to successful cancer treatment is tumour resistance to chemotherapy. White blood cells called macrophages often infiltrate tumours in large numbers, and now appear to promote tumour chemoresistance.

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Figure 1: Macrophages promote tumour chemoresistance.


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Correspondence to Michele De Palma or Claire E. Lewis.

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De Palma, M., Lewis, C. Macrophages limit chemotherapy. Nature 472, 303–304 (2011).

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