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Structural biology

Finding the wet spots

The functions of proteins are critically coupled to their interplay with water, but determining the dynamics of most water molecules at protein surfaces hasn't been possible. A new spectroscopic method promises to change that.

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Figure 1: Crystallographic versus NMR views of protein hydration.

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Hilser, V. Finding the wet spots. Nature 469, 166–167 (2011). https://doi.org/10.1038/469166a

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