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Cancer

Tumour stem cells switch sides

Tumour stem cells are proposed to be the source of tumour cells. It now emerges that they also give rise to the endothelial cells that line the tumour vasculature, mediating tumour growth and metastasis. See Letters p.824 & p.829

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Figure 1: Tumour stem-like cells are multipotent.

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Bautch, V. Tumour stem cells switch sides. Nature 468, 770–771 (2010). https://doi.org/10.1038/468770a

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