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Stem cells

Troublesome memories

Methods for generating embryonic-like stem cells have been established. The focus now is on finding ways to coax these cells into matching their natural counterparts as closely as possible, should this be desired.

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Figure 1: An embryonic-stem-cell beauty contest.


  1. Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).

    CAS  Article  Google Scholar 

  2. Kim, K. et al. Nature 467, 285–290 (2010).

    ADS  CAS  Article  Google Scholar 

  3. Ji, H. et al. Nature 467, 338–342 (2010).

    ADS  CAS  Article  Google Scholar 

  4. Polo, J. M. et al. Nature Biotechnol. 28, 848–855 (2010).

    CAS  Article  Google Scholar 

  5. Hochedlinger, K. & Jaenisch, R. Nature 441, 1061–1067 (2006).

    ADS  CAS  Article  Google Scholar 

  6. Yamanaka, S. Cell Stem Cell 1, 39–49 (2007).

    CAS  Article  Google Scholar 

  7. Zhou, Q. et al. Nature 455, 627–632 (2010).

    ADS  Article  Google Scholar 

  8. Vierbuchen, T. et al. Nature 463, 1035–1041 (2010).

    ADS  CAS  Article  Google Scholar 

  9. Fu, J.-D. et al. Cell 142, 375–386 (2010).

    Article  Google Scholar 

  10. Singer, T., McConnell, M. J., Marchetto, M. C., Coufal, N. G. & Gage, F. H. Trends Neurosci. 33, 345–354 (2010).

    CAS  Article  Google Scholar 

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Zwaka, T. Troublesome memories. Nature 467, 280–281 (2010).

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