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Fluorination made easier

By putting the pieces of a chemical puzzle into the right order, a thorny problem in catalysis has been solved. This opens the door to syntheses of molecules that contain the useful trifluoromethyl group.

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Figure 1: Catalytic cycle for a trifluoromethylation reaction.


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Ritter, T. Fluorination made easier. Nature 466, 447–448 (2010).

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