Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Stem cells

Cues from steroid hormones

The steroid hormones oestrogen and progesterone have a role in sickness and in health. In breast tissue, both roles probably work through a single mechanism: controlling the number and activity of mammary stem cells.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Hormones and cells.

References

  1. Asselin-Labat, M.-L. et al. Nature 465, 798–802 (2010).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Joshi, P. A. et al. Nature 465, 803–807 (2010).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Pike, M. C., Spicer, D. V., Dahmoush, L. & Press, M. F. Epidemiol. Rev. 15, 17–35 (1993).

    Article  CAS  PubMed  Google Scholar 

  4. Lambe, M. et al. N. Engl. J. Med. 331, 5–9 (1994).

    Article  CAS  PubMed  Google Scholar 

  5. Brisken, C. et al. Proc. Natl Acad. Sci. USA 95, 5076–5081 (1998).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  6. Fata, J. E. et al. Cell 103, 41–50 (2000).

    Article  CAS  PubMed  Google Scholar 

  7. Jones, D. H. et al. Nature 440, 692–696 (2006).

    Article  ADS  CAS  PubMed  Google Scholar 

  8. Fernandez-Valdivia, R. et al. Dev. Biol. 328, 127–139 (2009).

    Article  CAS  PubMed  Google Scholar 

  9. Gonzalez-Suarez, E. et al. Mol. Cell. Biol. 27, 1442–1454 (2007).

    Article  CAS  PubMed  Google Scholar 

  10. Graham, J. D. et al. Endocrinology 150, 3318–3326 (2009).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lydon, J. Cues from steroid hormones. Nature 465, 695–696 (2010). https://doi.org/10.1038/465695a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/465695a

This article is cited by

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer