Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Sex bias in trials and treatment must end

Gender inequalities in biomedical research are undermining patient care. In the first of three related pieces, Alison M. Kim, Candace M. Tingen and Teresa K. Woodruff call on journals, funding agencies and researchers to give women parity with men, in studies and in the clinic.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

References

  1. Holden, C. Science 322, 219 (2008).

    Article  CAS  PubMed Central  Google Scholar 

  2. Harris, D. J. & Douglas, P. S. N. Engl. J. Med. 343, 475–480 (2000).

    Article  CAS  PubMed Central  Google Scholar 

  3. Kim E. S., Carrigan, T. P. & Menon, V. J. Am. Coll. Cardiol. 52, 672–673 (2008).

    Article  PubMed Central  Google Scholar 

  4. Geller, S. E., Adams, M. G. & Carnes, M. J. Womens Health (Larchmt) 15, 1123–1131 (2006).

    Article  Google Scholar 

  5. Yang, X. et al. Genome Res. 16, 995–1004 (2006).

    Article  CAS  PubMed Central  Google Scholar 

  6. Mostertz, W. et al. JAMA 303, 535–543 (2010).

    Article  CAS  PubMed Central  Google Scholar 

  7. Anderson, G. D. J. Womens Health (Larchmt) 14, 19–29 (2005).

    Article  ADS  Google Scholar 

  8. Zopf, Y. et al. Eur. J. Clin. Pharmacol. 64, 999–1004 (2008).

    Article  CAS  PubMed Central  Google Scholar 

  9. Mosca, L. et al. Circulation 111, 499–510 (2005).

    Article  PubMed Central  Google Scholar 

  10. Day, S. C., Cassel, C. K. & Kimball, H. R. Am. J. Med. 100, 375–379 (1996).

    Article  CAS  PubMed Central  Google Scholar 

  11. Henrich, J. B. & Viscoli, C. M. Acad. Med. 81, 476–482 (2006).

    Article  PubMed Central  Google Scholar 

  12. Lewis, V., Barnhart, J., Houghton, J. L. & Charney, P. Int. J. Cardiol. 139, 204–206 (2010).

    Article  PubMed Central  Google Scholar 

  13. Bristol-Gould, S., Desjardins, M. & Woodruff, T. K. Womens Health (Lond Engl) 6, 183–196 (2010).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

See related Opinions on page 689 and page 690, and Editorial on page 665.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kim, A., Tingen, C. & Woodruff, T. Sex bias in trials and treatment must end. Nature 465, 688–689 (2010). https://doi.org/10.1038/465688a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/465688a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing