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DNA repair

Decision at the break point

Many decisions affect the fate of damaged DNA — for example, how to repair the damage, or whether to repair it at all and instead let the damaged cell die. An intricate web of molecular interactions affects such decisions.

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Figure 1: Choosing the correct repair pathway for DNA double-strand breaks (DSBs).

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Boulton, S. Decision at the break point. Nature 465, 301–302 (2010). https://doi.org/10.1038/465301a

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