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Epigenomics

Methylation matters

Genome-wide maps of methylated cytosine bases at single-base-pair resolution in human cells reveal distinct differences between cell types. These maps provide a starting point to decode the function of this enigmatic mark.

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Figure 1: DNA methylation patterns differ between stem cells and differentiated cells1.

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Schübeler, D. Methylation matters. Nature 462, 296–297 (2009). https://doi.org/10.1038/462296a

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