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Cancer

Deconstructing oncogenesis

Transformation of normal cells into cancer cells entails concerted changes in the expression of many genes. Identifying which of those genes are crucial will provide insight into the mechanisms underlying malignancy.

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Figure 1: Cooperation response genes.

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Luo, J., Elledge, S. Deconstructing oncogenesis. Nature 453, 995–996 (2008). https://doi.org/10.1038/453995a

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