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Biochemistry

Molecular cloaking devices

Protease enzymes cut other proteins into pieces, but some can be blocked by inhibitors. One such inhibitor binds to the substrate rather than the enzyme, suggesting a new tactic for drug discovery.

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Figure 1: Targets for enzyme inhibition.

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Kodadek, T. Molecular cloaking devices. Nature 453, 861–862 (2008). https://doi.org/10.1038/453861a

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