Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Molecular biology

Power sequencing

Advances in DNA-sequencing technology provide unprecedented insight into the entire collection of four genomes' transcribed sequences. They herald a new era in the study of gene regulation and genome function.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: mRNA-Seq.
Figure 2: Determining mRNA expression levels with mRNA-Seq.

References

  1. Wilhelm, B. T. et al. Nature 453, 1239–1243 (2008).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Nagalakshmi, U. et al. Science 10.1126/science.1158441 (2008).

  3. Lister, R. et al. Cell 133, 523–536 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Mortazavi, A., Williams, B. A., McCue, K., Schaeffer, L. & Wold, B. Nature Methods 10.1038/nmeth.1226 (2008).

  5. Cloonan, N. et al. Nature Methods 10.1038/nmeth.1223 (2008).

  6. Adams, M. D. et al. Science 252, 1651–1656 (1991).

    Article  ADS  CAS  PubMed  Google Scholar 

  7. Wold, B. & Myers, R. M. Nature Methods 5, 19–21 (2008).

    Article  CAS  PubMed  Google Scholar 

  8. Campbell, P. J. et al. Nature Genet. 40, 722–729 (2008).

    Article  CAS  PubMed  Google Scholar 

  9. Hodges, E. et al. Nature Genet. 39, 1522–1527 (2007).

    Article  CAS  PubMed  Google Scholar 

  10. Zerbino, D. R. & Birney, E. Genome Res. 18, 821–829 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Graveley, B. Power sequencing. Nature 453, 1197–1198 (2008). https://doi.org/10.1038/4531197b

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/4531197b

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing