Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Molecular motors

A step dissected

Nature volume 450, pages 625–626 (2007)Cite this article

The motor protein kinesin 'walks' by alternately advancing its two motor structural domains. A cutting-edge, single-molecule fluorescence technique reveals further details of this stepping mechanism.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Positioning of fluorescent sensors on a walking kinesin molecule.

References

  1. Mori, T., Vale, R. D. & Tomishige, M. Nature 450, 750–754 (2007).

    Article  ADS  CAS  Google Scholar 

  2. Richardson, D. N., Simmons, M. P. & Reddy, S. N. BMC Genomics 7, 18 (2006).

    Article  Google Scholar 

  3. Schnitzer, M. J. & Block, S. M. Nature 388, 386–390 (1997).

    Article  ADS  CAS  Google Scholar 

  4. Svoboda, K. et al. Nature 365, 721–727 (1993).

    Article  ADS  CAS  Google Scholar 

  5. Block, S.M. Biophys. J. 92, 2986–2995 (2007).

    Article  ADS  CAS  Google Scholar 

  6. Hackney, D. D. Proc. Natl Acad. Sci. USA 91, 6865–6869 (1994).

    Article  ADS  CAS  Google Scholar 

  7. Asenjo, A. B., Weinberg, Y. & Sosa, H. Nature Struct. Mol. Biol. 13, 648–654 (2006).

    Article  CAS  Google Scholar 

  8. Yildiz, A. et al. Science 303, 676–678 (2004).

    Article  ADS  CAS  Google Scholar 

  9. Alonso, M. C. et al. Science 316, 120–123 (2007).

    Article  ADS  CAS  Google Scholar 

  10. Kawaguchi, K. & Ishiwata, S. Science 291, 667–669 (2001).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Zeynep Ökten and Manfred Schliwa are at the Institute for Cell Biology and the Center for Integrated Protein Science, University of Munich, Schillerstraße 42, 80336 Munich, Germany. schliwa@med.uni-muenchen.de ,

    Zeynep Ökten & Manfred Schliwa

Authors
  1. Zeynep Ökten
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Manfred Schliwa
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ökten, Z., Schliwa, M. A step dissected. Nature 450, 625–626 (2007). https://doi.org/10.1038/450625a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/450625a

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing