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Structural biology

Unexpected opening

Cell membranes contain channels that open to allow ions into cells. The structure of a sodium ion channel helps explain how it opens in response to protons, and settles a long-standing debate about its composition.

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Figure 1: Proposed mechanism for sodium-ion channel opening.

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Canessa, C. Unexpected opening. Nature 449, 293–294 (2007). https://doi.org/10.1038/449293a

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