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Molecular medicine

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The inability to efficiently deliver small interfering RNAs to target organs hinders their therapeutic application. So a demonstration of siRNA delivery to a notoriously difficult organ — the brain — is very exciting indeed.

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Figure 1: Binding and uptake of peptide-conjugated siRNA by neuronal cells3.

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Cantin, E., Rossi, J. Entry granted. Nature 448, 33–34 (2007). https://doi.org/10.1038/448033a

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