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Stem cells

Good, bad and reformable

The ability of stem cells to continuously supply vast numbers of cells is magnificent, but it can be devastating if it runs amok, as in some tumours. So what makes a normal stem cell turn bad, and can it be redeemed?

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Figure 1: PTEN regulates signal transduction and cancer development.

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Janzen, V., Scadden, D. Good, bad and reformable. Nature 441, 418–419 (2006). https://doi.org/10.1038/441418b

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