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Membrane biology

Permutations of permeability

The first glimpse into the molecular basis of how sodium ions are transported across cell membranes by ion channels shows that cation-selective channels are variations on potassium channels.

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Figure 1: Structure of the KcsA potassium ion channel.
Figure 2: Mechanism of ion selectivity.

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Zagotta, W. Permutations of permeability. Nature 440, 427–429 (2006). https://doi.org/10.1038/440427a

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