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The manifold faces of DNA

When it comes to making shapes out of DNA, the material is there, and its properties are understood. What was missing was a convincing, universal design scheme to allow our capabilities to unfold to the full.

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Figure 1: Give us a smile.


  1. Rothemund, P. W. K. Nature 440, 297–302 (2006).

    ADS  CAS  Article  Google Scholar 

  2. Watson, J. D. & Crick, F. H. Nature 171, 737–738 (1953).

    ADS  CAS  Article  Google Scholar 

  3. Breslauer, K. J., Frank, R., Blocker, H. & Marky, L. A. Proc. Natl Acad. Sci. USA 83, 3746–3750 (1986).

    ADS  CAS  Article  Google Scholar 

  4. Zuker, M. Nucleic Acids Res. 31, 3406–3415 (2003).

    CAS  Article  Google Scholar 

  5. Seeman, N. C. Nature 421, 427–431 (2003).

    ADS  MathSciNet  Article  Google Scholar 

  6. Yan, H., Park, S. H., Finkelstein, G., Reif, J. H. & LaBean, T. H. Science 301, 1882–1884 (2003).

    ADS  CAS  Article  Google Scholar 

  7. Rothemund, P., Papadakis, N. & Winfree, E. PLoS Biol. 2, e424 (2004).

    Article  Google Scholar 

  8. Shih, W., Quispe, J. & Joyce, G. Nature 427, 618–621 (2004).

    ADS  CAS  Article  Google Scholar 

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Smith, L. The manifold faces of DNA. Nature 440, 283–284 (2006).

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