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Beyond ‘substantial equivalence’

Nature volume 401, pages 525–526 (1999)Cite this article

Showing that a genetically modified food is chemically similar to its natural counterpart is not adequate evidence that it is safe for human consumption.

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References

  1. Food Additives and the Consumer Appendix I, 41–43 (European Commission, Brussels, 1980).

  2. Strategies for Assessing the Safety of Foods Produced by Biotechnology (WHO, Geneva, 1991).

  3. Bowers, J. et al. Science 285, 1562–1565 (1999).

    Article  CAS  Google Scholar 

  4. Masood, E. Nature 398, 98 (1999).

    ADS  PubMed  Google Scholar 

  5. Safety Evaluation of Foods Derived by Modern Biotechnology (OECD, Paris, 1993).

  6. Lydon, J., & Duke, S. O. Pestic. Sci. 25, 361–374 (1989).

    Article  CAS  Google Scholar 

  7. Padgette, S. R. et al. J. Nutr. 126, 702–716 (1996).

    Article  CAS  Google Scholar 

  8. Kuiper, H. A. et al. Food Safety Evaluation of Genetically Modified Foods as a Basis for Market Introduction (Ministry of Economic Affairs, The Hague, 1998).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Epidemiology and Public Health, University College London, WC1E 6BT, London, UK

    Eric Brunner

  2. GeneWatch UK, The Courtyard, Whitecross Road, Tideswell, Derbyshire, SK17 8NY, Buxton, UK

    Sue Mayer

  3. SPRU–Science and Technology Policy Research, Mantell Building, University of Sussex, BN1 9RF, Brighton, UK

    Erik Millstone

Authors
  1. Erik Millstone
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  2. Eric Brunner
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  3. Sue Mayer
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Corresponding author

Correspondence to Erik Millstone.

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Millstone, E., Brunner, E. & Mayer, S. Beyond ‘substantial equivalence’. Nature 401, 525–526 (1999). https://doi.org/10.1038/44006

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