Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Neuroscience

Genomics reaches the synapse

A genomic survey uses innovative genetics to make neurons susceptible to RNA-mediated gene inactivation. The results implicate many genes in communication at the synapse between neurons and muscle.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Signal transmission at the neuromuscular junction (the synapse).

References

  1. Fire, A. Nature 391, 806–811 (1998).

    Article  ADS  CAS  Google Scholar 

  2. Sieburth, D. et al. Nature 436, 510–517 (2005).

    Article  ADS  CAS  Google Scholar 

  3. Fraser, A. G. et al. Nature 408, 325–330 (2000).

    Article  ADS  CAS  Google Scholar 

  4. Gönczy, P. et al. Nature 408, 331–336 (2000).

    Article  ADS  Google Scholar 

  5. Kennedy, S., Wang, D. & Ruvkun, G. Nature 427, 645–649 (2004).

    Article  ADS  CAS  Google Scholar 

  6. Wang, D. et al. Nature 436, 593–597 (2005).

    Article  ADS  CAS  Google Scholar 

  7. Nguyen, M. et al. Genetics 140, 527–535 (1995).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Ashrafi, K. et al. Nature 421, 268–272 (2003).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bargmann, C. Genomics reaches the synapse. Nature 436, 473–474 (2005). https://doi.org/10.1038/436473a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/436473a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing