Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Developmental biology

Asymmetrical threat averted

The somites are embryonic elements that give rise to the muscles, skeleton and some skin layers of the trunk. They form in a symmetrical fashion, but to do so they must be shielded from asymmetrical cues.

Your institute does not have access to this article

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: Maintaining symmetrical somitogenesis.


  1. Kawakami, Y., Raya, Á., Raya, R. M., Rodríguez-Esteban, C. & Izpisúa Belmonte, J. C. Nature 435, 165–171 (2005).

    ADS  CAS  Article  PubMed  Google Scholar 

  2. Vermot, J. & Pourquié, O. Nature 435, 215–220 (2005).

    ADS  CAS  Article  PubMed  Google Scholar 

  3. Vermot, J. et al. Science doi:10.1126/science.1108363 (2005).

  4. Tanaka, Y., Okada, Y. & Hirokawa, N. Nature 435, 172–177 (2005).

    ADS  CAS  Article  PubMed  Google Scholar 

  5. Levin, M. Mech. Dev. 122, 3–25 (2005).

    CAS  Article  PubMed  Google Scholar 

  6. Pourquié, O. Int. J. Dev. Biol. 47, 597–603 (2003).

    PubMed  Google Scholar 


  8. Zhang, X. M., Ramalho-Santos, M. & McMahon, A. P. Cell 105, 781–792 (2001).

    CAS  Article  PubMed  Google Scholar 

  9. Essner, J. J. et al. Development 132, 1247–1260 (2005).

    CAS  Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

Hornstein, E., Tabin, C. Asymmetrical threat averted. Nature 435, 155–156 (2005).

Download citation

  • Published:

  • Issue Date:

  • DOI:

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing