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Diabetes

Outfoxing insulin resistance?

Resistance to insulin predisposes people to diabetes; it is characterized by increased storage of fats and a failure to stop glucose synthesis. The molecular underpinnings of these effects have been uncovered.

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Figure 1: Model for insulin signalling in the liver.

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Montminy, M., Koo, SH. Outfoxing insulin resistance?. Nature 432, 958–959 (2004). https://doi.org/10.1038/432958a

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