Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Diabetes

Outfoxing insulin resistance?

Resistance to insulin predisposes people to diabetes; it is characterized by increased storage of fats and a failure to stop glucose synthesis. The molecular underpinnings of these effects have been uncovered.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Model for insulin signalling in the liver.

References

  1. Wolfrum, C., Asilmaz, E., Luca, E., Friedman, J. M. & Stoffel, M. Nature 432, 1027–1032 (2004).

    Article  ADS  CAS  Google Scholar 

  2. Spiegelman, B. M. & Heinrich, R. Cell 119, 157–167 (2004).

    Article  CAS  Google Scholar 

  3. Saltiel, A. & Kahn, C. R. Nature 414, 799–806 (2001).

    Article  ADS  CAS  Google Scholar 

  4. White, M. Mol. Cell. Biochem. 182, 3–11 (1998).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Montminy, M., Koo, SH. Outfoxing insulin resistance?. Nature 432, 958–959 (2004). https://doi.org/10.1038/432958a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/432958a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing