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An inflammatory link

The NF-κB protein is a key player in inflammation. It now seems that it might also activate signalling pathways, in both cancer cells and tumour-associated inflammatory cells, that promote malignancy.

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Figure 1: Opposing effects of the NF-κB protein in normal tissues and in cancer.


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Balkwill, F., Coussens, L. An inflammatory link. Nature 431, 405–406 (2004).

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