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Molecular biology

Cohesins slip sliding away

Cohesin complexes have a central role in cell division, mediating the association between sister chromosomes. It now seems that cohesin binding is dynamic, adapting to changes in gene transcription.

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Figure 1: The ChIP–chip technique used by Lengronne et al.3 and Glynn et al.4.
Figure 2: Cohesins associate with zones of convergent transcription.

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Ross, K., Cohen-Fix, O. Cohesins slip sliding away. Nature 430, 520–521 (2004). https://doi.org/10.1038/430520b

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