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Molecular biology

Cohesins slip sliding away

Nature volume 430, pages 520–521 (2004)Cite this article

Cohesin complexes have a central role in cell division, mediating the association between sister chromosomes. It now seems that cohesin binding is dynamic, adapting to changes in gene transcription.

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Figure 1: The ChIP–chip technique used by Lengronne et al.3 and Glynn et al.4.
Figure 2: Cohesins associate with zones of convergent transcription.

References

  1. Haering, C. H. & Nasmyth, K. BioEssays 25, 1178–1191 (2003).

    Article  CAS  Google Scholar 

  2. Campbell, J. L. & Cohen-Fix, O. 27, 492–495 (2002).

  3. Lengronne, A. et al. Nature 430, 573–578 (2004).

    Article  ADS  CAS  Google Scholar 

  4. Glynn, E. F. et al. PLoS Biol. 2, e259 (2004).

    Article  Google Scholar 

  5. Megee, P. C., Mistrot, C., Guacci, V. & Koshland, D. Mol. Cell 4, 445–450 (1999).

    Article  CAS  Google Scholar 

  6. Blat, Y. & Kleckner, N. Cell 98, 249–259 (1999).

    Article  CAS  Google Scholar 

  7. Tanaka, T., Cosma, M. P., Wirth, K. & Nasmyth, K. Cell 98, 847–858 (1999).

    Article  CAS  Google Scholar 

  8. Ciosk, R. et al. Mol. Cell 5, 243–254 (2000).

    Article  CAS  Google Scholar 

  9. Weber, S. A. et al. PLoS Biol. 2, e260 (2004).

    Article  Google Scholar 

  10. Bernard, P. & Allshire, R. Trends Cell Biol. 12, 419–424 (2002).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Laboratory of Molecular and Cellular Biology, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, Bethesda, 20892, Maryland, USA

    Karen E. Ross & Orna Cohen-Fix

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  1. Karen E. Ross
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  2. Orna Cohen-Fix
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Ross, K., Cohen-Fix, O. Cohesins slip sliding away. Nature 430, 520–521 (2004). https://doi.org/10.1038/430520b

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