Cellular signalling pathways depend on the proper activation and inactivation of mediators. New structural information reveals an unusual mechanism by which one such mediator, Rap1, is switched off.
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Rehmann, H., Bos, J. Thumbs up for inactivation. Nature 429, 138–139 (2004). https://doi.org/10.1038/429138a
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DOI: https://doi.org/10.1038/429138a
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