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Cancer

Kip moving

The p27Kip1 protein inhibits cell proliferation, helping to prevent tumours developing. We now know that it also affects cell migration, by regulating Rho proteins. Does this function influence tumour progression?

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Figure 1: Dual function of a tumour suppressor.

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Collard, J. Kip moving. Nature 428, 705–708 (2004). https://doi.org/10.1038/428705a

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  • DOI: https://doi.org/10.1038/428705a

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