Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Molecular Motors

Turning the ATP motor

A long-standing question regarding ATP synthase — a cellular energy-generator — has been which direction it spins in when generating ATP. Some elegant experiments have revealed the answer.

Your institute does not have access to this article

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: The binding-change model for F0F1 ATP synthase.

References

  1. Itoh, H. et al. Nature 427, 465–468 (2004).

    ADS  CAS  Article  Google Scholar 

  2. Boyer, P. D., Cross, R. L. & Momsen, W. Proc. Natl Acad. Sci. USA 70, 2837–2839 (1973).

    ADS  CAS  Article  Google Scholar 

  3. Kayalar, C., Rosing, J. & Boyer, P. D. J. Biol. Chem. 252, 2486–2491 (1977).

    CAS  PubMed  Google Scholar 

  4. Boyer, P. D. & Kohlbrenner, W. E. in Energy Coupling in Photosynthesis (eds Selman, B. & Selman-Reiner, S.) 231–240 (Elsevier North-Holland, New York, 1981).

    Google Scholar 

  5. Boekema, E. J., Ubbink-Kok, T., Lolkema, J. S., Brisson, A. & Konings, W. N. Proc. Natl Acad. Sci. USA 94, 14291–14293 (1997).

    ADS  CAS  Article  Google Scholar 

  6. Wilkens, S., Zhou, J., Nakayama, R., Dunn, S. D. & Capaldi, R. A. J. Mol. Biol. 295, 387–391 (2000).

    CAS  Article  Google Scholar 

  7. Hermolin, J., Dmitriev, O. Y., Zhang, Y. & Fillingame, R. H. J. Biol. Chem. 274, 17011–17016 (1999).

    CAS  Article  Google Scholar 

  8. Abrahams, J. P., Leslie, A. G., Lutter, R. & Walker, J. E. Nature 370, 621–628 (1994).

    ADS  CAS  Article  Google Scholar 

  9. Duncan, T. M., Bulygin, V. V., Zhou, Y., Hutcheon, M. L. & Cross, R. L. Proc. Natl Acad. Sci. USA 92, 10964–10968 (1995).

    ADS  CAS  Article  Google Scholar 

  10. Sabbert, D., Engelbrecht, S. & Junge, S. Nature 381, 623–625 (1996).

    ADS  CAS  Article  Google Scholar 

  11. Noji, H., Yasuda, R., Yoshida, M. & Kinosita, K. Jr Nature 386, 299–302 (1997).

    ADS  CAS  Article  Google Scholar 

  12. Zhou, Y., Duncan, T. M. & Cross, R. L. Proc. Natl Acad. Sci. USA 94, 10583–10587 (1997).

    ADS  CAS  Article  Google Scholar 

  13. Sabbert, D. & Junge, W. Proc. Natl Acad. Sci. USA 94, 2312–2317 (1997).

    ADS  CAS  Article  Google Scholar 

  14. Adachi, K. et al. Proc. Natl Acad. Sci. USA 97, 7243–7247 (2000).

    ADS  CAS  Article  Google Scholar 

  15. Diez, M. et al. Nature Struct. Mol. Biol. 11, 135–141 (2004).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Cross, R. Turning the ATP motor. Nature 427, 407–408 (2004). https://doi.org/10.1038/427407b

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/427407b

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing