The genetics of development can often explain the genesis of cancer. This now seems to be true for cancers of the gut, but the patterns of gene expression in these tumours tell a tale with a twist.
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Scott, M. A twist in a hedgehog's tale. Nature 425, 781–782 (2003). https://doi.org/10.1038/425780a
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DOI: https://doi.org/10.1038/425780a
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Hedgehog pathway activation in human transitional cell carcinoma of the bladder
British Journal of Cancer (2012)