Lack of oxygen causes the cells of certain tumours to spread to new locations. It also activates a homing mechanism that enables the migrating cells to target specific organs.
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References
Pennacchietti, S. et al. Cancer Cell 3, 347–361 (2003).
Bottaro, D. P. & Liotta, L. A. Nature 423, 593–595 (2003).
Staller, P. et al. Nature 425, 307–311 (2003).
Kaelin, W. G. Jr Nature Rev. Cancer 2, 673–682 (2002).
Homey, B., Muller, A. & Zlotnik, A. Nature Rev. Immunol. 2, 175–184 (2002).
Muller, A. et al. Nature 410, 50–56 (2001).
Kang, Y. et al. Cancer Cell 3, 537–549 (2003).
Tachibana, K. et al. Nature 393, 591–594 (1998).
Salcedo, R. et al. Am. J. Pathol. 154, 1125–1135 (1999).
Zeelenberg, I. S., Ruuls-Van Stalle, L. & Roos, E. Cancer Res. 63, 3833–3839 (2003).
Bernards, R. & Weinberg, R. A. Nature 418, 823 (2002).
Hynes, R. O. Cell 113, 821–823 (2003).
Bernards, R. & Weinberg, R. A. Nature 419, 560 (2002).
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Bernards, R. Cues for migration. Nature 425, 247–248 (2003). https://doi.org/10.1038/425247a
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DOI: https://doi.org/10.1038/425247a
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