Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Neurobiology

A new way to network

Guidance molecules called semaphorins ensure that nerve cells grow in the correct direction during development. It now appears that one semaphorin interacts with integrin proteins to produce another effect.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Effects of semaphorins on the development of the nervous system.

References

  1. Tessier-Lavigne, M. & Goodman, C. S. Science 274, 1123–1133 (1996).

    Article  ADS  CAS  Google Scholar 

  2. Pasterkamp, R. J. & Kolodkin, A. L. Curr. Opin. Neurobiol. 13, 79–89 (2003).

    Article  CAS  Google Scholar 

  3. Pasterkamp, R. J., Peschon, J. J., Spriggs, M. K. & Kolodkin, A. L. Nature 424, 398–405 (2003).

    Article  ADS  Google Scholar 

  4. Tamagnone, L. et al. Cell 99, 71–80 (1999).

    Article  CAS  Google Scholar 

  5. Milner, R. & Campbell, I. L. J. Neurosci. Res. 69, 286–291 (2002).

    Article  CAS  Google Scholar 

  6. Ivankovic-Dikic, I., Gronroos, E., Blaukat, A., Barth, B. U. & Dikic, I. Nature Cell Biol. 2, 574–581 (2000).

    Article  CAS  Google Scholar 

  7. Forcet, C. et al. Nature 417, 443–447 (2002).

    Article  ADS  CAS  Google Scholar 

  8. Hopker, V. H., Shewan, D., Tessier-Lavigne, M., Poo, M. & Holt, C. Nature 401, 69–73 (1999).

    Article  ADS  CAS  Google Scholar 

  9. Serini, G. et al. Nature 424, 391–397 (2003).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Patrick Mehlen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mehlen, P. A new way to network. Nature 424, 381–382 (2003). https://doi.org/10.1038/424381a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/424381a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing