Chromosome rearrangements within species are thought to contribute to reproductive isolation between species. This has now been shown directly by unrearranging yeast chromosomes to break down a species barrier.
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Wolfe, K. Speciation reversal. Nature 422, 25–26 (2003). https://doi.org/10.1038/422025a
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DOI: https://doi.org/10.1038/422025a
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