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Structural biology

Calcium callisthenics

The Ca2+-ATPase is one of the best characterized of the pumps that move ions across cell membranes. The latest snapshot of the pump in another of its many conformations is a major step in understanding its dynamics.

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Figure 1: The basic reaction cycle of Ca2+-ATPase.
Figure 2: Structure and function in a Ca2+ pump.

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References

  1. Toyoshima, C. & Nomura, H. Nature 418, 605–611 (2002).

    CAS  Article  Google Scholar 

  2. Toyoshima, C., Nakasako, M., Nomura, H. & Ogawa, H. Nature 405, 647–655 (2000).

    CAS  Article  Google Scholar 

  3. MacLennan, D. H., Rice, W. J. & Green, N. M. J. Biol. Chem. 272, 28815–28818 (1997).

    CAS  Article  Google Scholar 

  4. Zhang, P. et al. Nature 392, 835–839 (1998).

    CAS  Article  Google Scholar 

  5. Mintz, E. & Guillain, F. Biochim. Biophys. Acta 1318, 52–70 (1997).

    CAS  Article  Google Scholar 

  6. Levy, D. et al. J. Biol. Chem. 265, 19524–19534 (1990).

    CAS  PubMed  Google Scholar 

  7. de Meis, L. & Vianna, A. L. Annu. Rev. Biochem. 48, 275–292 (1979).

    CAS  Article  Google Scholar 

  8. Myung, J. & Jencks, W. P. FEBS Lett. 278, 35–37 (1991).

    CAS  Article  Google Scholar 

  9. Clarke, D. M. et al. J. Biol. Chem. 264, 11246–11251 (1989).

    CAS  PubMed  Google Scholar 

  10. Vilsen, B. & Andersen, J. P. Biochemistry 37, 10961–10971 (1998).

    CAS  Article  Google Scholar 

Download references

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Green, N., MacLennan, D. Calcium callisthenics. Nature 418, 598–599 (2002). https://doi.org/10.1038/418598b

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