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Full circle to cobbled brain

A biochemical link between certain congenital muscular dystrophies and the associated brain malformation known as cobblestone lissencephaly has been elusive. But it looks as if that link has been found.

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Figure 1: Congenital muscular dystrophy and α-dystroglycan3.
Figure 2: Cobblestone lissencephaly and α-dystroglycan4.


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Correspondence to M. Elizabeth Ross.

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Ross, M. Full circle to cobbled brain. Nature 418, 376–377 (2002).

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