Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Medicine

Anti-malarial mosquitoes?

Researchers have generated genetically altered mosquitoes with a reduced ability to transmit the malaria parasite in the lab. This is an important proof of principle, but there's still a long road ahead.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Life cycles of the malaria parasite.

References

  1. Ito, J., Ghosh, A., Moreira, L. A., Wimmer, E. A. & Jacobs-Lorena, M. Nature 417, 452–455 (2002).

    Article  ADS  CAS  Google Scholar 

  2. Bremen, J. Am. J. Trop. Med. Hyg. 64 (Suppl.), 1–11 (2001).

    Article  Google Scholar 

  3. Curtis, C. F. & Lines, J. D. Parasitol. Today 16, 119–121 (2000).

    Article  CAS  Google Scholar 

  4. Zieler, H. & Dvorak, J. A. Proc. Natl Acad. Sci. USA 97, 11516–11521 (2000).

    Article  ADS  CAS  Google Scholar 

  5. Han, Y. S., Thompson, J., Kafatos, F. C. & Barillas-Mury, C. EMBO J. 19, 6030–6040 (2000).

    Article  CAS  Google Scholar 

  6. Ghosh, A. K., Ribolla, P. E. M. & Jacobs-Lorena, M. Proc. Natl Acad. Sci. USA 98, 13278–13281 (2001).

    Article  ADS  CAS  Google Scholar 

  7. De Lara Capurro, M. et al. Am. J. Trop. Med. Hyg. 62, 427–433 (2000).

    Article  Google Scholar 

  8. Jasinskiene, N. et al. Proc. Natl Acad. Sci. USA 95, 3743–3747 (1998).

    Article  ADS  CAS  Google Scholar 

  9. Catteruccia, F. et al. Nature 405, 959–962 (2000).

    Article  ADS  CAS  Google Scholar 

  10. Kokoza, V. et al. Proc. Natl Acad. Sci. USA 97, 9144–9149 (2000).

    Article  ADS  CAS  Google Scholar 

  11. James, A. A. et al. Parasitologia 41, 461–471 (1999).

    CAS  Google Scholar 

  12. http://www.ensembl.org/Anopheles_gambiae

  13. http://www.ncbi.nlm.nih.gov:80/cgi-bin/Entrez/map_search?chr=agambiae.inf

  14. International Human Genome Sequencing Consortium Nature 409, 860–921 (2001).

  15. Venter, J. C. et al. Science 291, 1304–1351 (2001).

    Article  ADS  CAS  Google Scholar 

  16. http://PlasmoDB.org

  17. http://www.ncbi.nlm.nih.gov/Malaria

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lycett, G., Kafatos, F. Anti-malarial mosquitoes?. Nature 417, 387–388 (2002). https://doi.org/10.1038/417387a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/417387a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing