Many human disorders — a well-known example being Alzheimer's disease — are characterized by the misfolding and aggregation of key proteins. New small-molecule drugs may help to destabilize these aggregates.
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Iversen, L. Small drugs lead the attack. Nature 417, 231–233 (2002). https://doi.org/10.1038/417231a
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DOI: https://doi.org/10.1038/417231a