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Huntington's disease

Accomplices to neuronal death

The shaky movements of people with Huntington's disease are caused by death of a specific group of nerve cells. One culprit — the mutant huntingtin protein — is well known. Another has now been discovered.

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Figure 1: Possible functions of the normal and mutant huntingtin protein.

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Correspondence to Mark P. Mattson.

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Mattson, M. Accomplices to neuronal death. Nature 415, 377–378 (2002). https://doi.org/10.1038/415377a

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