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Development of a mathematical model for the prediction of the area of venous leak

International Journal of Impotence Research volume 13, pages 236–239 (2001)Cite this article

Abstract

Erectile dysfunction (ED) is an increasingly prevalent medical problem, affecting up to 50% of men aged between 40 and 70-y-old. Many cases are vasculogenic and some of these stem from the inability of the penis to store blood during erection due to leak into the venous system, termed corporo-venocclusive dysfunction (CVOD). The area of leakage during erection could be the most direct measure of erectile function but has not been investigated before. We have developed a simple mathematical model to determine the area of leak during erection and have tested it on data from both normal men (n=3) and men with venogenic impotence (n=16) undergoing dynamic infusion cavernosometry (DIC). The area of leak in the impotent group is significantly greater than in normal men at intracorporal pressures above 30 mmHg and reaches a plateau between 60 and 90 mmHg. Based on this study, we suggest that it may be necessary only to perform DIC at intracorporal pressures between 60 and 90 mmHg.

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Authors and Affiliations

  1. Department of Urology, Loyola University Medical Center and Research Service, Hines Veterans Administration Hospital, Maywood, IL, USA

    JP Mulhall & MS Damaser

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  1. JP Mulhall
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  2. MS Damaser
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Correspondence to JP Mulhall.

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Mulhall, J., Damaser, M. Development of a mathematical model for the prediction of the area of venous leak. Int J Impot Res 13, 236–239 (2001). https://doi.org/10.1038/sj.ijir.3900699

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  • DOI: https://doi.org/10.1038/sj.ijir.3900699

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