Isothermal titration calorimetry is a useful tool for the characterization of antibodies and antibody-related products, which uses heat as a detection medium, circumventing the problems associated with other analytical methods.
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References
Freire, E., Mayorga, O. L. & Straume, M. Anal. Chem. 62, 950A–959A (1990).
Hensley, P. Structure 4, 367–373 (1996).
Lakowicz, J. R. in Principles of Fluorescence Spectroscopy (Plenum, New York, 1983).
Goldberg, M. E. & Djavadi-Ohaniance, L. Curr. Opin. Immunol. 2, 278–281 (1993).
Schuck, P. & Minton, A. Trends Biochem. Sci. 21, 458–460 (1996).
Phizicky, E. M. & Fields, S. Microbiol. Rev. 59, 94–123 (1995).
Bundle, D. R. & Sigurskjold, B. W. Meth. Enzymol. 247, 288–305 (1994).
Fisher, H. F. & Singh, N. Meth. Enzymol. 259, 194–221 (1995).
Wiseman, T., Williston, S., Brandts, J. F. & Lin, L.-N. Anal. Biochem. 179, 5434–5441 (1993).
Kelley, R. F. et al. Biochemistry 31, 5434–5441 (1992).
Kelley, R. F. & O'Connell, M. P. Biochemistry 32, 6828–6835 (1993).
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Livingstone, J. Antibody characterization by isothermal titration calorimetry. Nature 384, 491–492 (1996). https://doi.org/10.1038/384491a0
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DOI: https://doi.org/10.1038/384491a0
