Fears that biochemical ratchets as explanations of muscle contraction (among other things) would contradict the Second Law of Thermodynamics have been stilled by an interesting counter-example.
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Maddox, J. Directed motion from random noise. Nature 369, 181 (1994). https://doi.org/10.1038/369181a0
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DOI: https://doi.org/10.1038/369181a0
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