Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Product Review
  • Published:

Protein images obtained by STM, AFM and TEM

Nature volume 358, pages 171–173 (1992)Cite this article

Scanning tunnelling microscopy and atomic force microscopy, one scanning the tunnelling current and the other the repulsive atomic force between sample and probe, can give high-quality surface topographies of proteins, which have been difficult to obtain by more conventional methods such as transmission electron microscopy.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Hoh, J. H., Lal, R., John, S. A., Revel, J.-P. & Arnsdorf, M. F. Science 253, 1405–1408 (1991).

    Article  ADS  CAS  Google Scholar 

  2. Driscoll, R. J., Youngquist, M. G. & Baldeschwieler, J. D. Nature 346, 294–296 (1990).

    Article  ADS  CAS  Google Scholar 

  3. Lindsay, S. M., Thundat, T., Nagahara, L., Knipping, U. & Rill, R. L. Science 244, 1063–1064 (1989).

    Article  ADS  CAS  Google Scholar 

  4. Dunlap, D. D. & Bustamante, C. Nature 342, 204–206 (1989).

    Article  ADS  CAS  Google Scholar 

  5. Arscott, P. G., Lee, G., Bloomfield, V. A. & Evans, D. F. Nature 339, 484–486 (1989).

    Article  ADS  CAS  Google Scholar 

  6. Hörber, J. K. H., Lang, C. A., Hänsch, T. W., Heckl, W. M. & Möhwald, H. Chem. Phys. Lett. 145, 151–158 (1988).

    Article  ADS  Google Scholar 

  7. Drake, B. et al. Science 243, 1586–1589 (1989).

    Article  ADS  CAS  Google Scholar 

  8. Wigren, R., Elwing, H., Erlandsson, R., Welin, S. & Lundström, I. FEBS Lett. 280, 225–228 (1991).

    Article  CAS  Google Scholar 

  9. Leatherbarrow, R. J., Stedman, M. & Wells T. N. C. J. molec. Biol. 221, 361–365 (1991).

    Article  CAS  Google Scholar 

  10. Vernetti, L. A., Nowlin, C. L. A., Hameroff, S. R., Gandolfi, A. J., Lee, Y. C. & Sarid, D. J. Vac. Sci. Technol. B9, 1223–1226 (1991).

    Article  CAS  Google Scholar 

  11. Weisenhorn, A. L. Biophys. J. 58, 1251–1258 (1990).

    Article  ADS  CAS  Google Scholar 

  12. Edstrom, R. D., Meinke, M. H., Yang, X., Yang, R., Elings, V. & Evans, D. F. Biophys. J. 58, 1437–1448 (1990).

    Article  CAS  Google Scholar 

  13. Edstrom, R. D., Meinke, M. H., Yang, X., Yang, R. & Evans, D. F. Biochemistry 28, 4939–4942 (1989).

    Article  CAS  Google Scholar 

  14. Osada, T., Nishigai, M., & Ikai, A. J. Ultrastruct. molec. Struct. Res. 101, 62–74 (1988).

    Article  CAS  Google Scholar 

  15. Ikai, A., Nishigai, M., Osada, T., Arakawa, H. & Kikuchi, M. J. Protein Chem. 6, 81–93 (1987).

    Article  CAS  Google Scholar 

  16. Clemmer, C. R. & Beebe, T. P. Jr Science 251, 640–642 (1991).

    Article  ADS  CAS  Google Scholar 

  17. Salmeron, M., Beebe, T., Odriozola, J., Wilson, T., Ogletree, D. F. & Siekhaus, W. J. Vac. Sci. Technol. A8, 635–641 (1990).

    Article  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculty of Bioscience and Biotechnology Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama, 227, Japan

    Hideo Arakawa, Kazuo Umemura & Atsushi Ikai

Authors
  1. Hideo Arakawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kazuo Umemura
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Atsushi Ikai
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Arakawa, H., Umemura, K. & Ikai, A. Protein images obtained by STM, AFM and TEM. Nature 358, 171–173 (1992). https://doi.org/10.1038/358171a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/358171a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing