Abstract
One approach to generating human monoclonal antibodies relies on the development of culture techniques allowing the long-term growth of most B lymphocytes, a property of the CD40 system.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Winter, G. & Milstein, C. Nature 349, 293–299 (1991).
Clark, E. A. & Ledbetter, J. A. Proc. natn. Acad. Sci. U.S.A. 83, 4494–4498 (1986).
Itoh, N. et al. Cell 66, 233–243 (1991).
Mallett, S. & Barclay, A. N. Immunol. Today 12, 220–222 (1991).
Banchereau, J., de Paoli, P., Vallé, A., Garcia, E. & Rousset, F. Science 251, 70–72 (1991).
Rousset, F., Garcia, E. & Banchereau, J. J. exp. Med. 173, 705–710 (1991).
Jabara, H. H., Fu, S. M., Geha, R. S. & Vercelli, D. J. exp. Med. 172, 1861–1864 (1990).
MacLennan, I. C. M., Liu, Y. J., Zhang, J. & Lane, P. J. L. Curr. Topics Microbiol. Immunol. 159, 37–60 (1990).
Huse, W. D. et al. Science 246, 1275–1281 (1989).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Banchereau, J., Rousset, F. Growing human B lymphocytes in the CD40 system. Nature 353, 678–679 (1991). https://doi.org/10.1038/353678a0
Issue Date:
DOI: https://doi.org/10.1038/353678a0
This article is cited by
-
Electrochemical immunoassay for the cancer marker LMP-1 (Epstein-Barr virus-derived latent membrane protein 1) using a glassy carbon electrode modified with Pd@Pt nanoparticles and a nanocomposite consisting of graphene sheets and MWCNTs
Microchimica Acta (2016)
-
Tuning of CD40–CD154 Interactions in Human B-Lymphocyte Activation: A Broad Array of In Vitro Models for a Complex In Vivo Situation
Archivum Immunologiae et Therapiae Experimentalis (2011)
-
Generation of B-cell chronic lymphocytic leukemia (B-CLL)-reactive T-cell lines and clones from HLA class I-matched donors using modified B-CLL cells as stimulators: implications for adoptive immunotherapy
Leukemia (2004)
-
Loss of Fas (CD95/APO-1) Regulatory Function Is an Important Step in Early MALT-Type Lymphoma Development
Laboratory Investigation (2001)
-
Development of human monoclonal antibodies: A review
Cytotechnology (1996)